Storm worm is industrialised automated infecting
The storm worm is making more binaries and infecting sites than any company can keep up with. During the first ten days of october they made 1400 different binaries (that is 140 variants a day) making it for the botnet hunter a total of 43,897+ unique binaries for the storm worm.
This means you will have to set your antivirus updates for critical machines to less than an hour and in fact limit your network traffic and email use to the strict business use. Sorry folks, this is an avalanche.